This procedure has been applied to the analysis of water.

The sample containing ⁹⁹Tc is equilibrated with ^95mTc, a gamma-emitting tracer. The technetium is separated from other elements by ferric and ferrous hydroxide precipitation from ammoniacal solutions. The sample is then passed through a commercially available column that selectively extracts Tc(VII) from a 0.1M HNO₃ solution. Technetium is purified, eluted from the column and counted directly in a suitable liquid scintillation cocktail. Typically, the sample is counted for 1h to simultaneously determine ⁹⁹Tc activity and the ^95mTc recovery.

Quench/efficiency calibration curves need to be established for the liquid scintillation spectrometer for both ^95mTc and ⁹⁹Tc.